How do the motor performance and muscle strength of aged mice change?
Maintained treadmill performance and improved some muscle mass and strength, aligning with exercise and muscle metabolism focus.[1] ↗
23-month-old mice; 31 days of AICAR administration
Research on aged mice cannot be extrapolated to exercise gains or general anti-aging effects in healthy humans.
View the Article Title and Full Citation+
Chronic treatment of old mice with AICAR reverses age-related changes in exercise performance and skeletal muscle gene expression.
FASEB BioAdvances · Volume and Issue Year 2025
First published 2025-01-29 · PMID 40060947
DOI 10.1096/fba.2024-00252







