ACE 031AC1

Images are illustrative. Actual specifications are as selected and confirmed in writing.

Growth Hormone & IGF-1

ACE 031

Muscle mass and muscle function

ACE 031 specifications and reference prices. Select a specification to add it to your cart.

1mg*10vials

Reference priceUS$70

For laboratory research only. Not for human or veterinary use.

COA 检测报告 / Reports

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SKUSpecification / packReference price (USD)
AC11mg*10vialsUS$70

Temporarily sold-out specifications can still be added to an inquiry to ask about restocking. An inquiry is not an order or an agreed price.

RESEARCH FOCUS

Main Uses & FAQs

This page organizes directly relevant information on ACE 031 regarding muscle mass and muscle function. First, review the research questions and findings, then verify the population or species, study formulations, and scope of interpretation.

Main TopicsMuscle mass · Muscle function
USAGE REFERENCE

ACE-031 · Usage reference (for research purposes).

The following presents common research-context references for reconstitution, storage, dosage and cycles. The following presents common references in research settings. This page does not constitute advice for use in humans or animals.

🧪Reconstitution

Suggested Diluent
Bacteriostatic Water (containing 0.9% benzyl alcohol); some peptides may use sterile water or acetic acid to aid dissolution. See the individual product descriptions.
Diluent Volume
Slowly introduce the diluent along the vial wall until the lyophilized powder is covered. A common example is 5 mg reconstituted with 2 mL of bacteriostatic water, yielding approximately 2.5 mg/mL. Referenced reconstitution volumes are approximately 1–2.5 mL, with 2 mL commonly used. It is suggested to select and record a fixed volume based on the COA supplied with the purchase.
Handling Notes
Introduce the diluent slowly along the vial wall rather than directly onto the lyophilized powder. Leave it for 60–90 seconds to dissolve naturally; do not shake vigorously.

💾Storage

Unreconstituted Lyophilized Powder
Refrigerate at 2–8°C, protected from light; avoid repeated freeze–thaw cycles.
After Reconstitution
Refrigerate at 2–8°C; a common recommendation is touse within 28 days; do not freeze.
Transport
For short periods, use insulated packaging with ice packs; avoid high temperatures and direct light.

📏Dosage Reference (Research)

Purpose / SettingCommon Reference
ExplanationMyostatin inhibitors, limited data.

Note: The above describes common research-context references, rather than clinical recommendations. Refer to the batch COA and research protocol. For research use only; not for human or animal use.

Research SummaryKey Findings

What research findings are there on ACE 031 regarding muscle mass and muscle function?

Improvement in lean body mass, muscle fiber cross-sectional area, and ex vivo muscle strength indicators. Other studies report: in higher dose group, 29-day increase in lean body mass and thigh muscle volume.[1] ↗ [2] ↗

Before ReadingStudy populations, species, formulations and delivery conditions each have a defined scope. Research on an ingredient does not establish that this site's product batches have been validated for efficacy in humans or veterinary use.
3 Main ReferencesSorted by First Publication Date ↓
Animal Study2026REF. 01

How do the muscle mass and strength indicators of marmosets change?

Research Findings

Improvement in lean body mass, muscle fiber cross-sectional area, and ex vivo muscle strength indicators.[1] ↗

Study Design

Common marmosets; ACE-031 administration

Scope & Limitations

Non-human primates; product must correspond to ActRIIB-Fc fusion protein.

View the Article Title and Full Citation+

ACE-031, a soluble activin type IIB receptor, increases muscle mass and strength in the common marmoset (Callithrix jacchus).

Cadena SM, Bogdanovich S, Khurana TS, Pullen A, Pearsall RS, Curran E, Faucette R, Lane J, Seehra J, Lachey JL, Mizener AD, Pistilli EE.

PLoS One · Volume and Issue Year 2026
First published 2026-02-13 · PMID 41686840
DOI 10.1371/journal.pone.0342666

Human Study2013 · Historical basic researchREF. 02

How were lean body mass and muscle volume in early human trials?

Research Findings

Higher dose group showed increased lean body mass and thigh muscle volume after 29 days.[2] ↗

Study Design

48 healthy postmenopausal women randomized single-dose study.

Scope & Limitations

2013, short-term; does not represent exercise function or long-term therapeutic benefits.

View the Article Title and Full Citation+

A single ascending-dose study of muscle regulator ACE-031 in healthy volunteers.

Attie KM, Borgstein NG, Yang Y, Condon CH, Wilson DM, Pearsall AE, Kumar R, Willins DA, Seehra JS, Sherman ML.

Muscle & nerve · Volume/Issue Year 2013
First published on 2012-11-21 · PMID 23169607
DOI 10.1002/mus.23539

Animal Study2010 · Historical basic researchREF. 03

Changes in animal skeletal muscle weight and muscle fiber area?

Research Findings

Multiple groups showed increases in skeletal muscle mass and muscle fiber cross-sectional area.[3] ↗

Study Design

C57BL/6 mice; ACE-031 administered for 28 days

Scope & Limitations

2010; Changes in muscle mass cannot replace evidence of human exercise function.

View the Article Title and Full Citation+

Administration of a soluble activin type IIB receptor promotes skeletal muscle growth independent of fiber type.

Cadena SM, Tomkinson KN, Monnell TE, Spaits MS, Kumar R, Underwood KW, Pearsall RS, Lachey JL.

Journal of Applied Physiology (Bethesda, Md. : 1985) · Volume and Issue Year 2010
First published on 2010-05-13 · PMID 20466801
DOI 10.1152/japplphysiol.00866.2009

i

Currently, 3 original studies related to the theme of this page have been selected. The number of studies includes different designs, populations, or preparations, not commercial clinical efficacy ratings. This page is a usage-oriented positive data selection, not a systematic review or dosing recommendation. Historical studies, combination preparations, and special models are all separately indicated.

GO DEEPER

What Questions Do These Studies Address?

Compare study populations, findings and scope.

↗
QUESTIONS, ANSWERED

ACE 031 · Frequently Asked Questions.

What research findings are there on ACE 031 regarding muscle mass and muscle function?+

Improvement in lean body mass, muscle fiber cross-sectional area, and ex vivo muscle strength indicators. Other studies report: in higher dose group, 29-day increase in lean body mass and thigh muscle volume.[1] ↗ [2] ↗

Does an increase in lean body mass from ACE-031 mean improved muscle function?+

cannot be directly equated. Early human studies mainly looked at lean body mass and thigh muscle volume, while animal studies included different muscle function indicators; it is also necessary to confirm that the product is the corresponding fusion protein.[2] ↗ [1] ↗

ACE 031—these conclusions apply to which study populations?+

Common marmosets; ACE-031 administration; single-dose study in 48 healthy postmenopausal women; C57BL/6 mice; ACE-031 administration for 28 days. Non-human primates; product must correspond to ActRIIB-Fc fusion protein.[1] ↗ [2] ↗ [3] ↗

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