What research findings exist regarding VIP in pulmonary vascular and airway-related studies?
After VIP intervention, mean pulmonary artery pressure decreased, and indicators such as cardiac output improved.[1] ↗
Currently Selected 1 Original Study Related to the Theme of This Page. Fewer than 3 studies, the gap is retained, no other uses are added to fill the number. This page is a purposive collection of positive information, not a systematic review or dosage recommendation. Historical studies, combination formulations, and special models are separately indicated.
Comparison of study design and results
Results from different populations, species, materials, or follow-up times cannot be directly combined. The table below is a comparative summary of published data, not new experimental data.
| Literature | Study subjects and design | Observation and discovery | Scope of Explanation |
|---|---|---|---|
| 2003 · PMID 12727925 | 8 patients with primary pulmonary hypertension; historical exploratory study. | After VIP intervention, mean pulmonary artery pressure decreased, and indicators such as cardiac output improved. | 2003 Very minimal, non-confirmatory study; special clinical preparation and research conditions, does not represent effects for other lung diseases or general commercial products. |
References
What were the findings in early human studies on pulmonary hypertension?
After VIP intervention, mean pulmonary artery pressure decreased, and indicators such as cardiac output improved.[1] ↗
8 patients with primary pulmonary hypertension; historical exploratory study.
2003 Very minimal, non-confirmatory study; special clinical preparation and research conditions, does not represent effects for other lung diseases or general commercial products.
View the Article Title and Full Citation＋
Vasoactive intestinal peptide as a new drug for treatment of primary pulmonary hypertension.
The Journal of Clinical Investigation · Volume, Issue, Year 2003
First published 2003-05-01 · PMID 12727925
DOI 10.1172/JCI17500
Common issues and corresponding evidence
What research findings exist regarding VIP in pulmonary vascular and airway-related studies?＋
After VIP intervention, mean pulmonary artery pressure decreased, and indicators such as cardiac output improved.[1] ↗
Can pulmonary vascular studies of VIP represent all airway uses?＋
: Not allowed. The small historical human study here was conducted on primary pulmonary arterial hypertension to observe hemodynamics; it cannot be extrapolated to general respiratory health, infections, or efficacy for all lung diseases.[1] ↗
VIP—these conclusions apply to which study populations?＋
8 patients with primary pulmonary hypertension; historical exploratory study. Very small, non-confirmatory study in 2003; special clinical formulation under research conditions, does not represent efficacy for other lung diseases or general commercial use.[1] ↗
VIP
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