SS-31
2S10 · 10mg · 2026-10-21 · N/A
COA PDF ↗
2S5Images are illustrative. Actual specifications are as selected and confirmed in writing.
Longevity & Mitochondrial Research
SS-31
Mitochondrial function, muscle capacity and fatigue
SS-31 specifications and reference prices. Select a specification to add it to your cart.
5mg/vial x 10vials
Reference priceUS$105.88
For laboratory research only. Not for human or veterinary use.
COA 检测报告 / Reports
Compare all specifications & reference prices
| SKU | Specification / pack | Reference price (USD) |
|---|---|---|
| 2S5 | 5mg/vial x 10vials | US$105.88 |
| 2S10 | 10mg/vial x 10vials | US$200 |
| 2S50 | 50mg/vial x 10vials | US$564.71 |
Temporarily sold-out specifications can still be added to an inquiry to ask about restocking. An inquiry is not an order or an agreed price.
Explore Longevity & Mitochondrial Research ↗ · View all products
RESEARCH FOCUS
Main Uses & FAQs
This page organizes directly related information on SS-31 regarding mitochondrial function, muscle performance, and fatigue. First, look at research questions and findings, then verify the population or species, study formulations, and scope of interpretation.
Main TopicsMitochondrial function · muscle capacity · fatigue
USAGE REFERENCE
SS-31 (Elamipretide) · Usage reference (for research use)
The following presents common research-context references for reconstitution, storage, dosage and cycles. The following presents common references in research settings. This page does not constitute advice for use in humans or animals.
🧪Reconstitution
- Suggested Diluent
- Bacteriostatic Water (containing 0.9% benzyl alcohol); some peptides may use sterile water or acetic acid to aid dissolution. See the individual product descriptions.
- Diluent Volume
- Slowly introduce the diluent along the vial wall until the lyophilized powder is covered. A common example is 5 mg reconstituted with 2 mL of bacteriostatic water, yielding approximately 2.5 mg/mL. Referenced reconstitution volumes are approximately 1–2.5 mL, with 2 mL commonly used. It is suggested to select and record a fixed volume based on the COA supplied with the purchase.
- Handling Notes
- Introduce the diluent slowly along the vial wall rather than directly onto the lyophilized powder. Leave it for 60–90 seconds to dissolve naturally; do not shake vigorously.
💾Storage
- Unreconstituted Lyophilized Powder
- Refrigerate at 2–8°C, protected from light; avoid repeated freeze–thaw cycles.
- After Reconstitution
- Refrigerate at 2–8°C; a common recommendation is touse within 28 days; do not freeze.
- Transport
- For short periods, use insulated packaging with ice packs; avoid high temperatures and direct light.
📏Dosage Reference (Research)
| Purpose / Setting | Common Reference |
|---|---|
| Explanation | Mitochondrial protection, injection study |
Note: The above describes common research-context references, rather than clinical recommendations. Refer to the batch COA and research protocol. For research use only; not for human or animal use.
References
Read the Full Research Review ↗Research SummaryKey Findings
What research findings exist for SS-31 regarding mitochondrial function, muscle capacity, and fatigue?
Improves overall skeletal muscle and some single-fiber contraction indicators. Additionally, research reports: improves muscle anti-fatigue capacity and some cardiac functions, and slows the accumulation of frailty.[1] ↗ [2] ↗
Before ReadingStudy populations, species, formulations and delivery conditions each have a defined scope. Research on an ingredient does not establish that this site's product batches have been validated for efficacy in humans or veterinary use.
Animal Study2026REF. 01
How does skeletal muscle performance change in diseased rats?
Research Findings
Improves overall skeletal muscle and some single-fiber contraction indicators.[1] ↗
Study Design
HFpEF rats; 12-week intervention
Scope & Limitations
Disease animal models cannot be extrapolated to improved exercise performance in healthy humans.
View the Article Title and Full Citation＋
Targeting Mitochondrial Dysfunction With Elamipretide (SS-31) Improves Skeletal Muscle Performance in a HFpEF Rat Model.
Circulation. Heart failure · Volume and issue year 2026
First published 2026-06-15 · PMID 42290373
DOI 10.1161/CIRCHEARTFAILURE.126.014397
Animal Study2025REF. 02
What does the anti-fatigue research in aged mice indicate?
Research Findings
Improves muscle anti-fatigue capacity and some cardiac functions, and slows the accumulation of frailty.[2] ↗
Study Design
Aged C57BL/6J mice; 8-week elamipretide treatment
Scope & Limitations
No significant reversal of epigenetic or transcriptional age was detected; cannot promote reversing biological age; not equivalent to effects in healthy humans.
View the Article Title and Full Citation＋
The Mitochondria-Targeted Peptide Therapeutic Elamipretide Improves Cardiac and Skeletal Muscle Function During Aging Without Detectable Changes in Tissue Epigenetic or Transcriptomic Age.
Aging Cell · Volume and Year 2025
First published 2025-03-13 · PMID 40080911
DOI 10.1111/acel.70026
Human Study2024REF. 03
What was observed in the long-term follow-up of Barth syndrome?
Research Findings
Walking distance, fatigue, and some cardiac indicators improved relative to the baseline of the open-label extension period.[3] ↗
Study Design
Barth syndrome patients; TAZPOWER up to 168 weeks open-label extension
Scope & Limitations
Only 10 patients entered the extension phase, while 8 completed it; There was no placebo comparison during the extension period, and fatigue resistance was not extrapolated to ordinary people.
View the Article Title and Full Citation＋
Long-term efficacy and safety of elamipretide in patients with Barth syndrome: 168-week open-label extension results of TAZPOWER.
Genetics in Medicine: official journal of the American College of Medical Genetics · Volume, Issue, Year 2024
First published 2024-04-08 · PMID 38602181
DOI 10.1016/j.gim.2024.101138
Currently, 3 original studies related to the theme of this page have been selected. The number of studies includes different designs, populations, or preparations, not commercial clinical efficacy ratings. This page is a usage-oriented positive data selection, not a systematic review or dosing recommendation. Historical studies, combination preparations, and special models are all separately indicated.
GO DEEPER
↗What Questions Do These Studies Address?
Compare study populations, findings and scope.
SS-31 · Frequently Asked Questions.
What research findings exist for SS-31 regarding mitochondrial function, muscle capacity, and fatigue?＋
Improves overall skeletal muscle and some single-fiber contraction indicators. Additionally, research reports: improves muscle anti-fatigue capacity and some cardiac functions, and slows the accumulation of frailty.[1] ↗ [2] ↗
What population is the anti-fatigue data for SS-31 derived from?＋
Human long-term data from small Barth syndrome population; other muscle performance studies included aged mice and disease rats. Cannot promise anti-fatigue effects in general healthy people based on this.[3] ↗ [2] ↗ [1] ↗
SS-31—these conclusions apply to which study populations?＋
HFpEF rats; 12-week intervention; aged C57BL/6J mice; 8-week elamipretide treatment; Barth syndrome patients; TAZPOWER maximum 168-week open-label extension. Disease animal models cannot be extrapolated to improved exercise performance in healthy humans.[1] ↗ [2] ↗ [3] ↗
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