PNC-27PN5

Images are illustrative. Actual specifications are as selected and confirmed in writing.

Repair & Recovery Research

PNC-27

Tumor targeting and antitumor research

PNC-27 specifications and reference prices. Select a specification to add it to your cart.

5mg/vial x 10vials
Reference priceUS$105

For laboratory research only. Not for human or veterinary use.

COA 检测报告 / Reports

Compare all specifications & reference prices
SKUSpecification / packReference price (USD)
PN55mg/vial x 10vialsUS$105
PN1010mg/vial x 10vialsUS$152

Temporarily sold-out specifications can still be added to an inquiry to ask about restocking. An inquiry is not an order or an agreed price.

RESEARCH FOCUS

Main Uses & FAQs

This page organizes directly relevant information on PNC-27 regarding tumor targeting and antitumor research. First, look at the research questions and findings, then verify the population or species, study preparations, and scope of interpretation.

Main TopicsTumor Targeting · Anti-tumor research
USAGE REFERENCE

PNC-27 · Usage reference (for research purposes)

The following presents common research-context references for reconstitution, storage, dosage and cycles. The following presents common references in research settings. This page does not constitute advice for use in humans or animals.

🧪Reconstitution

Suggested Diluent
Bacteriostatic Water (containing 0.9% benzyl alcohol); some peptides may use sterile water or acetic acid to aid dissolution. See the individual product descriptions.
Diluent Volume
Slowly introduce the diluent along the vial wall until the lyophilized powder is covered. A common example is 5 mg reconstituted with 2 mL of bacteriostatic water, yielding approximately 2.5 mg/mL. Referenced reconstitution volumes are approximately 1–2.5 mL, with 2 mL commonly used. It is suggested to select and record a fixed volume based on the COA supplied with the purchase.
Handling Notes
Introduce the diluent slowly along the vial wall rather than directly onto the lyophilized powder. Leave it for 60–90 seconds to dissolve naturally; do not shake vigorously.

💾Storage

Unreconstituted Lyophilized Powder
Refrigerate at 2–8°C, protected from light; avoid repeated freeze–thaw cycles.
After Reconstitution
Refrigerate at 2–8°C; a common recommendation is touse within 28 days; do not freeze.
Transport
For short periods, use insulated packaging with ice packs; avoid high temperatures and direct light.

📏Dosage Reference (Research)

Purpose / SettingCommon Reference
ExplanationTumor targeted research

Note: The above describes common research-context references, rather than clinical recommendations. Refer to the batch COA and research protocol. For research use only; not for human or animal use.

Research SummaryKey Findings

What research findings exist regarding PNC-27 in tumor targeting and anti-tumor studies?

PNC-27 reduces leukemia cells and stem cells while retaining partial normal hematopoietic function.[1] ↗

Before ReadingStudy populations, species, formulations and delivery conditions each have a defined scope. Research on an ingredient does not establish that this site's product batches have been validated for efficacy in humans or veterinary use.
1 Main ReferencesSorted by First Publication Date ↓
Animal Study2020 · Historical basic researchREF. 01

What were the findings of targeted studies in leukemia animal models?

Research Findings

PNC-27 reduces leukemia cells and stem cells while retaining partial normal hematopoietic function.[1] ↗

Study Design

Human/mouse AML transplant animal model

Scope & Limitations

2020 animal tumor model, cannot promote anti-cancer effect in humans.

View the Article Title and Full Citation+

Targeting cell membrane HDM2: A novel therapeutic approach for acute myeloid leukemia.

Wang H, Zhao D, Nguyen LX, Wu H, Li L, Dong D, Troadec E, Zhu Y, Hoang DH, Stein AS, Al Malki M, Aldoss I, Lin A, Ghoda LY, McDonald T, Pichiorri F, Carlesso N, Kuo YH, Zhang B, Jin J, Marcucci G.

Leukemia · Volume, issue, year 2020
First published 2019-07-23 · PMID 31337857
DOI 10.1038/s41375-019-0522-9

i

Currently Selected 1 Original Study Related to the Theme of This Page. Fewer than 3 studies, the gap is retained, no other uses are added to fill the number. This page is a purposive collection of positive information, not a systematic review or dosage recommendation. Historical studies, combination formulations, and special models are separately indicated.

GO DEEPER

What Questions Do These Studies Address?

Compare study populations, findings and scope.

↗
QUESTIONS, ANSWERED

PNC-27 · Frequently Asked Questions.

What research findings exist regarding PNC-27 in tumor targeting and anti-tumor studies?+

PNC-27 reduces leukemia cells and stem cells while retaining partial normal hematopoietic function.[1] ↗

Has anti-tumor research on PNC-27 demonstrated anti-cancer effects in humans?+

No. The core research on this page is on leukemia animal models and mechanisms, and cannot be considered evidence of efficacy or cure in humans.[1] ↗

PNC-27—these conclusions apply to which study populations?+

Human/mouse AML transplant animal model. 2020 animal tumor model, cannot promote human anticancer efficacy.[1] ↗

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