KPVKP5

Images are illustrative. Actual specifications are as selected and confirmed in writing.

Repair & Recovery Research

KPV

Inflammation and intestinal mucosal barrier

KPV specifications and reference prices. Select a specification to add it to your cart.

5mg/vial x 10vials
Reference priceUS$93.94

For laboratory research only. Not for human or veterinary use.

COA 检测报告 / Reports

Compare all specifications & reference prices
SKUSpecification / packReference price (USD)
KP55mg/vial x 10vialsUS$93.94
KP1010mg/vial x 10vialsUS$154.55

Temporarily sold-out specifications can still be added to an inquiry to ask about restocking. An inquiry is not an order or an agreed price.

RESEARCH FOCUS

Main Uses & FAQs

This page organizes directly related information on inflammation and intestinal mucosal barrier of KPV. First, look at the research questions and findings, then verify the population or species, study preparations, and scope of interpretation.

Main TopicsInflammation · Intestinal mucosal barrier
USAGE REFERENCE

KPV · Usage reference (for research purposes)

The following presents common research-context references for reconstitution, storage, dosage and cycles. The following presents common references in research settings. This page does not constitute advice for use in humans or animals.

🧪Reconstitution

Suggested Diluent
Bacteriostatic Water (containing 0.9% benzyl alcohol); some peptides may use sterile water or acetic acid to aid dissolution. See the individual product descriptions.
Diluent Volume
Slowly introduce the diluent along the vial wall until the lyophilized powder is covered. A common example is 5 mg reconstituted with 2 mL of bacteriostatic water, yielding approximately 2.5 mg/mL. Referenced reconstitution volumes are approximately 1–2.5 mL, with 2 mL commonly used. It is suggested to select and record a fixed volume based on the COA supplied with the purchase.
Handling Notes
Introduce the diluent slowly along the vial wall rather than directly onto the lyophilized powder. Leave it for 60–90 seconds to dissolve naturally; do not shake vigorously.

💾Storage

Unreconstituted Lyophilized Powder
Refrigerate at 2–8°C, protected from light; avoid repeated freeze–thaw cycles.
After Reconstitution
Refrigerate at 2–8°C; a common recommendation is touse within 28 days; do not freeze.
Transport
For short periods, use insulated packaging with ice packs; avoid high temperatures and direct light.

📏Dosage Reference (Research)

Purpose / SettingCommon Reference
ReferenceAnti-inflammatory/intestine barrier studies, often combined with BPC/GHK

🔁Cycle

Record according to combination formula.

View the Complete Usage Guide Library →

Note: The above describes common research-context references, rather than clinical recommendations. Refer to the batch COA and research protocol. For research use only; not for human or animal use.

Research SummaryKey Findings

What research findings exist on KPV regarding inflammation and the intestinal mucosal barrier?

ProKPV responsive to inflammation improves delivery and enhances anti-inflammatory effects. Another study reports that KPV co-assembled with FK506 nanoparticles improves inflammation and intestinal barrier.[1] ↗ [2] ↗

Before ReadingStudy populations, species, formulations and delivery conditions each have a defined scope. Research on an ingredient does not establish that this site's product batches have been validated for efficacy in humans or veterinary use.
3 main theme articles · Identity/formulation needs verificationSorted by First Publication Date ↓
Animal Study2026REF. 01

How is the prodrug KPV studied for intestinal delivery and inflammation?

Research Findings

ProKPV that responds to inflammation improves delivery and enhances anti-inflammatory effects.[1] ↗

Study Design

Mouse colitis and acute lung injury; KPV prodrug

Scope & Limitations

Studies a chemically modified prodrug, not the prototype KPV direct administration.

View the Article Title and Full Citation+

Inflammation-triggered self-immolative conjugates enable oral peptide delivery by overcoming gastrointestinal barriers.

Cheng J, Wu P, Li C, Han Y, Sun M, Dou Y, Chen S, Zhang J.

Science Advances · Volume/Issue/Year 2026
First published 2026-01-14 · PMID 41533788
DOI 10.1126/sciadv.aea2989

Animal Study2024REF. 02

What research findings exist for KPV co-assembled with immunosuppressants?

Research Findings

KPV co-assembled with FK506 nanoparticles improves inflammation and intestinal barrier.[2] ↗

Study Design

DSS mice acute/chronic colitis

Scope & Limitations

Combined immunosuppressants and nano-delivery.

View the Article Title and Full Citation+

PepT1-targeted nanodrug based on co-assembly of anti-inflammatory peptide and immunosuppressant for combined treatment of acute and chronic DSS-induced ColitiS.

Zhang D, Jiang L, Yu F, Yan P, Liu Y, Wu Y, Yang X.

Frontiers in Pharmacology · Volume and Issue Year 2024
First published 2024-08-15 · PMID 39211778
DOI 10.3389/fphar.2024.1442876

Animal Study2022REF. 03

What does research on KPV combined with hydrogels indicate about the intestinal barrier?

Research Findings

PMSP-KPV hydrogel enhances local anti-inflammatory effects and mucosal barrier restoration.[3] ↗

Study Design

TNBS rat colitis; intrarectal administration

Scope & Limitations

Materials combined with delivery cannot be used as clinical evidence for regular KPV injections.

View the Article Title and Full Citation+

A KPV-binding double-network hydrogel restores gut mucosal barrier in an inflamed colon.

Zhao Y, Xue P, Lin G, Tong M, Yang J, Zhang Y, Ran K, Zhuge D, Yao Q, Xu H.

Acta Biomaterialia · Volume/Issue, 2022
First published 2022-03-01 · PMID 35245681
DOI 10.1016/j.actbio.2022.02.039

i

Currently, 3 original studies related to the theme of this page have been selected. The number of studies includes different designs, populations, or preparations, not commercial clinical efficacy ratings. This page is a usage-oriented positive data selection, not a systematic review or dosing recommendation. Historical studies, combination preparations, and special models are all separately indicated.

GO DEEPER

What Questions Do These Studies Address?

Compare study populations, findings and scope.

↗
QUESTIONS, ANSWERED

KPV · Frequently Asked Questions.

What research findings exist on KPV regarding inflammation and the intestinal mucosal barrier?+

ProKPV responsive to inflammation improves delivery and enhances anti-inflammatory effects. Another study reports that KPV co-assembled with FK506 nanoparticles improves inflammation and intestinal barrier.[1] ↗ [2] ↗

Do all intestinal barrier studies of KPV use regular KPV?+

No. Current data includes prodrugs, combined immunosuppressants, and hydrogel delivery, and should be interpreted separately; it cannot be regarded as the human efficacy of unmodified KPV injection.[1] ↗ [2] ↗ [3] ↗

KPV—these conclusions apply to which study populations?+

Mouse colitis and acute lung injury; KPV prodrug; DSS mouse acute/chronic colitis; TNBS rat colitis; intracolonic administration. The study is on chemically modified prodrugs, not direct administration of the prototype KPV.[1] ↗ [2] ↗ [3] ↗

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