ET10

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Longevity & Mitochondrial Research

Epithalon

Q: What research findings exist regarding Epithalon in aging, lifespan, and cellular aging mechanisms?

Epitalon在部分SAMP-1末期存活动物中延长生存，提供寿命研究线索。 另有研究报告：末10%存活者寿命及最大寿命增加，并减少部分染色体异常。 原始文献：https://pubmed.ncbi.nlm.nih.gov/15909815/, https://pubmed.ncbi.nlm.nih.gov/14501183/

Q: In Epithalon studies, is the maximum lifespan equal to the average lifespan?

不等于。某些小鼠研究报告末期存活者或最大寿命延长，但平均寿命并未增加；果蝇结果也不能换算成人体抗衰。 原始文献：https://pubmed.ncbi.nlm.nih.gov/14501183/, https://pubmed.ncbi.nlm.nih.gov/11087911/

Q: Epithalon—these conclusions apply to which study populations?

衰老加速小鼠；2005年历史研究；雌性Swiss来源SHR小鼠；2003年历史研究；果蝇；2000年历史研究。效果具有品系与指标限制；不是平均寿命普遍延长，更不是人体抗衰证据。 原始文献：https://pubmed.ncbi.nlm.nih.gov/15909815/, https://pubmed.ncbi.nlm.nih.gov/14501183/, https://pubmed.ncbi.nlm.nih.gov/11087911/

Aging, lifespan and cellular senescence mechanisms

Epithalon specifications and reference prices. Select a specification to add it to your cart.

10mg/vial x 10vials

Reference priceUS$109.09

For laboratory research only. Not for human or veterinary use.

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SKU	Specification / pack	Reference price (USD)
ET10	10mg/vial x 10vials	US$109.09
ET50	50mg/vial x 10vials	US$333.33

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RESEARCH FOCUS

Main Uses & FAQs

This page organizes directly related information on the aging, lifespan, and cellular senescence mechanisms of Epithalon. First, look at the research questions and findings, then verify the population or species, study preparations, and scope of interpretation.

Main TopicsAging · Lifespan and mechanisms of cellular aging

What research findings exist regarding Epithalon in aging, lifespan, and cellular aging mechanisms?↗In Epithalon studies, is the maximum lifespan equal to the average lifespan?↗Epithalon—these conclusions apply to which study populations?↗

References

Read the Full Research Review ↗

Research SummaryKey Findings

What research findings exist regarding Epithalon in aging, lifespan, and cellular aging mechanisms?

Epitalon extends survival in some late-stage SAMP-1 surviving animals, providing clues for lifespan research. Other research reports: the lifespan and maximum lifespan of the last 10% of survivors increased, and some chromosomal abnormalities were reduced.[1] ↗ [2] ↗

Before ReadingStudy populations, species, formulations and delivery conditions each have a defined scope. Research on an ingredient does not establish that this site's product batches have been validated for efficacy in humans or veterinary use.

3 Main ReferencesSorted by First Publication Date ↓

Animal Study2005 · Historical basic researchREF. 01

How do survival indicators in aging accelerated mice change?

Research Findings

Epitalon extends survival in some late-stage SAMP-1 animals, providing clues for lifespan research.[1] ↗

Study Design

Accelerated aging mice; 2005 historical study

Scope & Limitations

Effects are limited by strain and indicators; it is not a universal extension of average lifespan, and certainly not evidence of anti-aging in humans.

View the Article Title and Full Citation＋

[Effect of epitalon and melatonin on life span and spontaneous carcinogenesis in senescence accelerated mice (SAM)].

Anisimov VN, Popovich IG, Zabezhinskiĭ MA, Rozenfel'd SV, Khavinson VKh, Semenchenko AV, Iashin AI

Voprosy Onkologii · Volume and issue year 2005
First published 2005-01-01 · PMID 15909815
DOI not provided in the database

Animal Study2003 · Historical basic researchREF. 02

Are maximum lifespan and average lifespan improved simultaneously?

Research Findings

Lifespan and maximum lifespan increased in the last 10% survivors, and some chromosomal abnormalities were reduced.[2] ↗

Study Design

Female Swiss-derived SHR mice; 2003 historical study

Scope & Limitations

Average lifespan did not increase, maximum lifespan results cannot be used to replace average lifespan conclusions; not extrapolated to humans.

View the Article Title and Full Citation＋

Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice.

Anisimov VN, Khavinson VKh, Popovich IG, Zabezhinski MA, Alimova IN, Rosenfeld SV, Zavarzina NY, Semenchenko AV, Yashin AI

Biogerontology · Volume/Issue Year 2003
First published 2003-01-01 · PMID 14501183
DOI 10.1023/a:1025114230714

Animal Study2000 · Historical basic researchREF. 03

Which statements can fly lifespan studies support?

Research Findings

Adding Epitalon to developmental stage culture medium extended adult lifespan by 11%–16%.[3] ↗

Study Design

Fruit flies; historical study from 2000

Scope & Limitations

Only fruit flies and medication occurs during development; Cannot be inferred from anti-aging effects in adults.

View the Article Title and Full Citation＋

Effect of epitalon on the lifespan increase in Drosophila melanogaster.

Khavinson VK, Izmaylov DM, Obukhova LK, Malinin VV

Mechanisms of ageing and development · Volume/Issue Year 2000
First published 2000-12-01 · PMID 11087911
DOI 10.1016/s0047-6374(00)00217-7

Currently, 3 original studies related to the theme of this page have been selected. The number of studies includes different designs, populations, or preparations, not commercial clinical efficacy ratings. This page is a usage-oriented positive data selection, not a systematic review or dosing recommendation. Historical studies, combination preparations, and special models are all separately indicated.

QUESTIONS, ANSWERED

Epithalon · Frequently Asked Questions.

What research findings exist regarding Epithalon in aging, lifespan, and cellular aging mechanisms?＋

In Epithalon studies, is the maximum lifespan equal to the average lifespan?＋

Not equal. Some mouse studies report survivors at the end stage or extended maximum lifespan, but average lifespan did not increase; Drosophila results cannot be converted to human anti-aging.[2] ↗ [3] ↗

Epithalon—these conclusions apply to which study populations?＋

Aging accelerated mice; 2005 historical study; Female Swiss source SHR mice; 2003 historical study; Fruit fly; 2000 historical study. Effects are limited by strain and indicators; It is not a universal increase in average lifespan, nor is it evidence of human anti-aging.[1] ↗ [2] ↗ [3] ↗

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Epithalon

COA 检测报告 / Reports

Main Uses & FAQs

References

What research findings exist regarding Epithalon in aging, lifespan, and cellular aging mechanisms?

How do survival indicators in aging accelerated mice change?

[Effect of epitalon and melatonin on life span and spontaneous carcinogenesis in senescence accelerated mice (SAM)].

Are maximum lifespan and average lifespan improved simultaneously?

Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice.

Which statements can fly lifespan studies support?

Effect of epitalon on the lifespan increase in Drosophila melanogaster.

What Questions Do These Studies Address?

Epithalon · Frequently Asked Questions.

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