What does the study of left ventricular fibrosis in cardiomyopathy models indicate?
B7-33 reduces left ventricular fibrosis and improves some cardiovascular tissue indicators.[1] ↗
Mouse isoproterenol cardiomyopathy model
Preclinical; not equivalent to efficacy in human heart failure.
View the Article Title and Full Citation+
The single-chain relaxin mimetic, B7-33, maintains the cardioprotective effects of relaxin and more rapidly reduces left ventricular fibrosis compared to perindopril in an experimental model of cardiomyopathy.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie · Volume/Issue Year 2023
First published 2023-02-06 · PMID 36753958
DOI 10.1016/j.biopha.2023.114370







